HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 117773884, compound → HCID 178467142, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 117773884 | HCID 117773884 | — |
| Reactant | HCID 178452329 | HCID 178452329 | — |
| Product | HCID 178467142 | HCID 178467142 | 73% |
Reaction Steps
Following general procedure V, {4-[(3-acetyl-6-chloro-1,5-naphthyridin-4-yl)amino]-cyclohexyl}methyl methanesulfonate (170 mg, 0.42 mmol) was reacted with tert-butyl 4-[(trans-4-aminocyclohexyl)methyl]piperazine-1-carboxylate (93 mg, 0.50 mmol) to afford the desired product (150 mg, 73%) as a yellow solid. ESI MS m/z 502 [M+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09345709B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-8d6052adf27547ab9e9da35a49aac7fb |
| Source note | uspto-grants-2016_05 |