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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 526216Generated: October 30, 2026

Boc-DL-valine → HCID 178467149, compound

https://huagongshe.com/reaction/526216

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoc-DL-valineHCID 270655—
ReactantHCID 117774125HCID 117774125—
ProductHCID 178467149HCID 17846714965.7%

Reaction Steps

Following general procedure VI, 1-{4-[(4-aminocyclohexyl)amino]-6-chloro-1,5-naphthyridin-3-yl}ethanone dihydrochloride (300 mg, 0.94 mmol) was reacted with 2-[(tert-butoxycarbonyl)amino]-3-methylbutanoic acid (310 mg, 1.4 mmol) to afford the desired product (320 mg, 65%) as a white solid. ESI MS m/z 518 [M+H]+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09345709B2
Source datasetuspto-grants-2016_05
ORD IDord-8461c6a4ee464153917d575fb26f43a9
Source noteuspto-grants-2016_05