HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boc-DL-valine → HCID 178467149, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boc-DL-valine | HCID 270655 | — |
| Reactant | HCID 117774125 | HCID 117774125 | — |
| Product | HCID 178467149 | HCID 178467149 | 65.7% |
Reaction Steps
Following general procedure VI, 1-{4-[(4-aminocyclohexyl)amino]-6-chloro-1,5-naphthyridin-3-yl}ethanone dihydrochloride (300 mg, 0.94 mmol) was reacted with 2-[(tert-butoxycarbonyl)amino]-3-methylbutanoic acid (310 mg, 1.4 mmol) to afford the desired product (320 mg, 65%) as a white solid. ESI MS m/z 518 [M+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09345709B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-8461c6a4ee464153917d575fb26f43a9 |
| Source note | uspto-grants-2016_05 |