Methyl 4-Formylbenzoate → HCID 89601758, compound

Participants

Reaction Steps

To a solution of 5-bromo-2-methyl-1,2,3,4-tetrahydropyrimido[1,6-a]indole (0.254 g) in 8 mL of ether cooled at −78° C. was added t-BuLi (1.4 mL, 1.7 M in pentane) dropwise. After attiring at −78° C. for 15 min, a solution of methyl 4-formylbenzoate (0.200 g in 2 mL of ether) was added quickly by a syringe. The reaction mixture was wormed to r.t. over 10 min, and quenched with 10 mL of saturated aqueous solution of NH4Cl, and 20 mL of EtOAc was added. The solid was collected by filtration to give 0.2 g of the title compound as a white solid.

Provenance & Evidence