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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 526519Generated: October 27, 2026

N-benzyl-6-hydrazinylpyridine-3-carboxamide → HCID 178509610, compound

https://huagongshe.com/reaction/526519

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-benzyl-6-hydrazinylpyridine-3-carboxamideHCID 51370238—
ReactantEthyl 2-(2-chloro-4-cyanophenyl)-3-(dimethylamino)acrylateHCID 117601384—
ProductHCID 178509610HCID 178509610—

Reaction Steps

The title compound was prepared in a manner similar to Example 188 using ethyl 2-(2-chloro-4-cyanophenyl)-3-(dimethylamino)acrylate and N-benzyl-6-hydrazinylnicotinamide. 1H NMR (400 MHz, DMSO-d6) δ ppm 4.44 (d, J=5.8 Hz, 2H) 7.13-7.22 (m, 2H) 7.27 (d, J=4.3 Hz, 5H) 7.75 (d, J=8.3 Hz, 1H) 8.00 (s, 1H) 8.30-8.47 (m, 2H) 8.90 (s, 1H) 9.20 (t, J=5.3 Hz, 1H). MS m/z [M+H]+ 430.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09345713B2
Source datasetuspto-grants-2016_05
ORD IDord-19fc1727cbdf4b39a203449c4e85a506
Source noteuspto-grants-2016_05