反应详情

The title compound was prepared in a manner similar to Example 198 using 6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)nicotinic acid and 1-(2-methoxyethyl)cyclopropanamine. 1H NMR (400 MHz, DMSO-d6) δ ppm 0.57-0.73 (m, 4H) 1.79 (t, J=7.1 Hz, 2H) 3.14 (s, 3H) 3.39 (t, J=7.1 Hz, 2H) 3.79 (s, 3H) 7.37 (br. s., 1H) 7.44 (br. s., 1H) 7.99 (d, J=5.6 Hz, 1H) 8.31 (d, J=7.8 Hz, 2H) 8.57 (br. s., 1H) 8.77 (s, 1H) 8.79-8.84 (m, 1H) 13.52 (br. s., 1H). MS m/z 410 [M+H]+.