HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Methoxy-6-methylpyridin-4-YL)boronic acid → HCID 178495307, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Methoxy-6-methylpyridin-4-YL)boronic acid | HCID 67216047 | — |
| Reactant | 6-(4-bromo-5-methoxy-1H-pyrazol-1-yl)-N-(3-methoxypropyl)nicotinamide | HCID 117601269 | — |
| Product | HCID 178495307 | HCID 178495307 | — |
Reaction Steps
The title compound was prepared in a manner similar to Example 212 using 6-(4-bromo-5-methoxy-1H-pyrazol-1-yl)-N-(3-methoxypropyl)nicotinamide and (2-methoxy-6-methylpyridin-4-yl)boronic acid. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.71 (quin, J=6.6 Hz, 2H) 2.30 (s, 3H) 3.18 (s, 3H) 3.22-3.30 (m, 2H) 3.32 (t, J=6.3 Hz, 2H) 3.79 (s, 3H) 7.16 (br. s., 1H) 7.31 (br. s., 1H) 8.31 (br. s., 1H) 8.33-8.53 (m, 2H) 8.61 (br. s., 1H) 8.82 (s, 1H) 13.35 (br. s., 1H). MS m/z 398 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09345713B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-0e5ce7be3f6a432d8c0d9449aa7d3bd0 |
| Source note | uspto-grants-2016_05 |