1-(2-Methoxyethyl)cyclopropanamine hydrochloride → HCID 178494833, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to Example 200 using 6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and 1-(2-methoxyethyl)cyclopropanamine. 1H NMR (400 MHz, DMSO-d6) δ ppm 0.65-0.73 (m, 2H) 0.72-0.80 (m, 2H) 1.86 (t, J=7.1 Hz, 2H) 2.43 (s, 3H) 3.21 (s, 3H) 3.46 (t, J=6.9 Hz, 2H) 7.64 (dd, J=8.1, 1.5 Hz, 1H) 7.71 (s, 1H) 7.80 (d, J=8.1 Hz, 1H) 8.14 (s, 1H) 8.38 (br. s., 2H) 8.83 (s, 1H) 8.87 (t, J=1.5 Hz, 1H) 13.17 (br. s., 1H). MS m/z 418 [M+H]+.

Provenance & Evidence