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HRID526588

反应详情

EQUATION

反应方程式

HRID 526588 的结构方程式

REACTANTS

反应物

2
结构：COC1CCNCC1
HCID77666

4-Methoxypiperidine

C6H13NO

结构：Cc1c(-c2cnn(-c3ccc(C(=O)O)cn3)c2O)ccc(C#N)c1F
HCID178422218

未命名化合物

PRODUCTS

生成物

1
结构：COC1CCN(C(=O)c2ccc(-n3ncc(-c4ccc(C#N)c(F)c4C)c3O)nc2)CC1
HCID178493262

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a manner similar to Example 303 using 6-(4-(4-cyano-3-fluoro-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and 4-methoxypiperidine. 1H NMR (500 MHz, DMSO-d6) δ ppm 1.49 (br. s., 2H) 1.75-1.97 (m, 2H) 2.33 (d, J=1.95 Hz, 3H) 3.11-3.68 (m, 7H) 3.92 (br. s., 1H) 7.64 (br. s., 1H) 7.70-7.79 (m, 1H) 8.07 (d, J=7.81 Hz, 1H) 8.12-8.65 (m, 3H). ESI-MS m/z [M+H]+ 436.3.