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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 526619Generated: October 31, 2026

HCID 28937401, compound → HCID 178495120, compound

https://huagongshe.com/reaction/526619

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 28937401HCID 28937401—
ReactantHCID 178426451HCID 178426451—
ProductHCID 178495120HCID 178495120—

Reaction Steps

The title compound was prepared in a manner similar to Example 112 using 6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and (S)-4-methoxybutan-2-amine. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.19 (d, J=6.82 Hz, 3H) 1.67-1.77 (m, 1H) 1.77-1.88 (m, 1H) 2.44 (s, 3H) 3.23 (s, 3H) 3.39 (t, J=6.57 Hz, 2H) 4.06-4.20 (m, 1H) 7.67 (d, J=8.08 Hz, 1H) 7.73 (s, 1H) 7.78 (br. s., 1H) 8.17 (br. s., 1H) 8.43 (d, J=7.33 Hz, 3H) 8.89-8.95 (m, 1H) 13.16 (br. s., 1H); ESI-MS m/z [M+H]+ 406.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09345713B2
Source datasetuspto-grants-2016_05
ORD IDord-2d91cf5db30244559640d671b29947c8
Source noteuspto-grants-2016_05