HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Civetone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 17-oxocycloheptadec-8-ene-1-carboxylate | HCID 53673108 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Civetone | HCID 5315941 | — |
Reaction Steps
2-ethoxycarbonyl-9-cycloheptadecenone will be refluxed with about 10% NaOH in methanol for about 1 hour to give civetone. After completion of the reaction, the reaction mixture will be neutralized using about 10% sulfuric acid. The product will be extracted using ether and can be purified using silica-gel chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346729B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-00fc4ff0450f49bc9168967cb6cbe090 |
| Source note | uspto-grants-2016_05 |