HuagongsheHuagongshe Chemistry Print Report · For research reference only
Eslicarbazepine acetate → Oxcarbazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Eslicarbazepine acetate | HCID 179344 | — |
| Reactant | R-Licarbazepine | HCID 9816485 | — |
| Reactant | Eslicarbazepine | HCID 9881504 | — |
| Reactant | (R)-Licarbazepine Acetate | HCID 10590023 | — |
| Product | Oxcarbazepine | HCID 34312 | — |
Reaction Steps
In an another embodiment, the invention provides a process for preparing (S)-(−)-10-acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide, or (R)-(+)-10-acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide from (S)-(+)-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide or (R)-(−)-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide, which are obtained by enantioselective reduction of 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide or derivatives thereof in presence of boronate esters.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346760B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-8e8e7db178ef4d04b51b910d62001f36 |
| Source note | uspto-grants-2016_05 |