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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 526907Generated: October 31, 2026

Methyl chloroformate → HCID 68007942, compound

https://huagongshe.com/reaction/526907

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl chloroformateHCID 6586—
Reactant(S)-2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoro-N-(1-(methylsulfonyl)pyrrolidin-3-yl)pyrimidin-4-amineHCID 68008525—
ProductHCID 68007942HCID 6800794252%

Reaction Steps

According to the procedure for compound 398 using methylchloroformate (20 mg, 0.21 mmol) afforded 13.6 mg (52% yield) of 476, as a trifluoroacetic acid salt after preparatory HPLC purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09345708B2
Source datasetuspto-grants-2016_05
ORD IDord-ba55c4226ddb4874a6b3f351d4cced12
Source noteuspto-grants-2016_05