HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → HCID 68008073, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | (S)-2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoro-N-(1-(methylsulfonyl)pyrrolidin-3-yl)pyrimidin-4-amine | HCID 68008525 | — |
| Product | HCID 68008073 | HCID 68008073 | 18% |
Reaction Steps
According to the procedure for compound 398 using acetyl chloride (45 uL, 0.64 mmol) afforded 4.2 mg (18% yield) of 480, as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09345708B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-8585bf6d60b845f3aa5122f89106a945 |
| Source note | uspto-grants-2016_05 |