HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methoxyacetyl chloride → HCID 68007907, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methoxyacetyl chloride | HCID 96623 | — |
| Reactant | (S)-2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoro-N-(1-(methylsulfonyl)pyrrolidin-3-yl)pyrimidin-4-amine | HCID 68008525 | — |
| Product | HCID 68007907 | HCID 68007907 | 33% |
Reaction Steps
According to the procedure for compound 398 using methoxyacetyl chloride (50 mg, 0.46 mmol) afforded 8.6 mg (33% yield) of 481, as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09345708B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-85f807d7fd62441e9f9f1c13e0d78457 |
| Source note | uspto-grants-2016_05 |