反应详情

To a solution of (1R,3S)-ethyl 3-(benzyloxycarbonylamino)cyclohexane-carboxylate, 18b, (14.0 g, 45.9 mmol) in ethanol (3 mL) was added Pd/C (wet, Degussa (2.4 g, 2.3 mmol). The mixture was evacuated and then stirred under atmosphere of nitrogen at room temperature overnight. The reaction mixture was filtered through a pad of celite and the resulting filtrate concentrated in vacuo to provide an oil that was used without further purification.

1. customThe mixture was evacuated
2. filtrationThe reaction mixture was filtered through a pad of celite
3. concentrationthe resulting filtrate concentrated in vacuo
4. customto provide an oil that
5. customwas used without further purification