HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminobenzoic Acid → HCID 90410908, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminobenzoic Acid | HCID 978 | — |
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | tert-Butyl methyl ether | HCID 15413 | — |
| Reactant | HCID 1115345 | HCID 1115345 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 90410908 | HCID 90410908 | — |
Reaction Steps
Mixing 4-amino benzoic acid and lithium hydroxide in DMAc, then adding 3,5-dibromo-6H-anthra[1,9-cd]isoxazol-6-one into the mixture at about 40-60° C. Stirring the reaction mixture for up to 24 hours. Adding MTBE to the reaction mixture. Filtering the solid and drying to get 4-((3-bromo-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl)amino)benzoic acid (Intermediate 5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346788B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-2611595dcb014b31adcf5f55e19e95c5 |
| Source note | uspto-grants-2016_05 |