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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 527146Generated: October 31, 2026

Tetrahydrofuran → HCID 71477447, compound

https://huagongshe.com/reaction/527146

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphosgeneHCID 94429—
ReactantHCID 86717345HCID 86717345—
ProductHCID 71477447HCID 7147744796%

Reaction Steps

A solution of 2-amino-2-(4-isopropyl-2-methoxyphenyl)-2H-inden-1,3-dione (0.80 g, 2.58 mmol) in anhydrous THF (20 ml) was added triphosgene (0.84 g, 2.84 mmol) and stirred for 15 min. The reaction mixture was concentrated and was dissolved in ethanol (20 ml) was stirred for 2 hrs at room temperature to afford the title compound (0.95 g, 96%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09346749B2
Source datasetuspto-grants-2016_05
ORD IDord-f6fb36ac244a412a9ad9ed900b756f26
Source noteuspto-grants-2016_05