HRID52729

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10820784

未命名化合物

结构：COC(=O)[C@@H](NC(=O)Oc1ccc([N+](=O)[O-])cc1)C(C)C

HCID15344176

Methyl N-[(4-nitrophenoxy)carbonyl]-L-valinate

C13H16N2O6

结构：COC(=O)[C@H](C)NC(=O)Oc1ccc([N+](=O)[O-])cc1

HCID54298210

未命名化合物

PRODUCTS

生成物

结构：COC(=O)[C@H](C)NC(=O)N(C)Cc1coc(C(C)C)n1

HCID10708114

未命名化合物

收率 66%

PROCEDURE

实验过程

Using the procedure of Example 1S, but replacing 2-isopropyl-4-(((N-methyl)amino)methyl)thiazole with 2-isopropyl-4-(((N-methyl)amino)methyl)-oxazole and relacing N-(((4-nitrophenyl)oxy)carbonyl)-L-valine methyl ester with N-(((4-nitrophenyl)oxy)carbonyl)-L-alanine methyl ester provided the desired compound in 66% yield. 1H NMR (CDCl3) δ1.32 (d, 6H), 1.42 (d, 3H), 2.96 (s, 3H), 3.05 (m, 1H), 3.75 (s, 3H), 4.30 (s, 2H), 4.47 (m, 1H), 5.80 (br d, 1H), 7.46 (s, 1H). Mass spectrum: (M+H)+ =284.