Bromine → HCID 86711614, compound

HRID 527345Notes

Reaction equation

HRID 527345 reaction equation
C(N=S(C1C=CC(CN[C:13]([C:15]2[C:20](=[O:21])[C:19]([Br:22])=[C:18]([CH3:23])[N:17]([C:24]3[N:25]([CH3:29])[N:26]=[CH:27][CH:28]=3)[CH:16]=2)=[O:14])=CC=1)(C)=O)#N.C(N=S(C1C=CC(CN[C:44](C2C(=O)C=C(C)N(C3N(C)N=CC=3)C=2)=[O:45])=CC=1)(C)=O)#N.BrBr>>[CH3:44][O:45][C:13]([C:15]1[C:20](=[O:21])[C:19]([Br:22])=[C:18]([CH3:23])[N:17]([C:24]2[N:25]([CH3:29])[N:26]=[CH:27][CH:28]=2)[CH:16]=1)=[O:14]

Participants

4

Reactant 3

HCID 24408BromineHCID 86711607HCID 86711607, compoundHCID 86711608HCID 86711608, compound

Product 1

HCID 86711614HCID 86711614, compound

Procedure

The title compound is prepared as described for preparation 4c, substituting preparation 4b with preparation 8.20a as starting material. ESI mass spectrum: [M+H]+=326 (bromine pattern); r.t. HPLC: 0.69 min (Z012_S04).

Workup

  1. customr.t
  2. custom0.69 min (Z012_S04)

Sources & evidence

ORD record
ord-56c61e954edc450e8fc6ef15065284a5
Source dataset
uspto-grants-2016_05
Patent number
US09346794B1

Reaction notes

Loading…