(4-(N-cyano-S-methylsulfonimidoyl)phenyl)methanamine → (4-(N-Cyano-S-ethylsulfonimidoyl)phenyl)methanamine

HRID 527347Notes

Reaction equation

HRID 527347 reaction equation
C(N=S(C1C=CC(CN)=CC=1)(C)=O)#N.[C:15]([N:17]=[S:18]([C:22]1[CH:39]=[CH:38][C:25]([CH2:26][N:27]2C(=O)C3C(=CC=CC=3)C2=O)=[CH:24][CH:23]=1)([CH2:20][CH3:21])=[O:19])#[N:16]>>[C:15]([N:17]=[S:18]([C:22]1[CH:39]=[CH:38][C:25]([CH2:26][NH2:27])=[CH:24][CH:23]=1)([CH2:20][CH3:21])=[O:19])#[N:16]

Participants

3

Reactant 2

HCID 86711611(4-(N-cyano-S-methylsulfonimidoyl)phenyl)methanamineHCID 867116162-(4-(N-cyano-S-ethylsulfonimidoyl)benzyl)isoindoline-1,3-dione

Product 1

HCID 86711617(4-(N-Cyano-S-ethylsulfonimidoyl)phenyl)methanamine

Procedure

The title compound is prepared in analogy to preparation 6d, substituting 2-(4-(N-cyano-S-methylsulfonimidoyl)benzyl)isoindoline-1,3-dione with 2-(4-(N-cyano-S-ethylsulfonimidoyl)benzyl)isoindoline-1,3-dione (preparation 13b). ESI mass spectrum: [M+H]+=224; r.t. HPLC: 0.52 min (Z011_S03).

Workup

  1. customr.t

Sources & evidence

ORD record
ord-122df9a87de0432d9859e2cf68db0022
Source dataset
uspto-grants-2016_05
Patent number
US09346794B1

Reaction notes

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