(4-(N-cyano-S-methylsulfonimidoyl)phenyl)methanamine → (5-(N-Cyano-S-methylsulfonimidoyl)pyridin-2-yl)methanamine

HRID 527356Notes

Reaction equation

HRID 527356 reaction equation
[C:1]([N:3]=[S:4]([C:7]1[CH:12]=[CH:11][C:10]([CH2:13][NH2:14])=C[CH:8]=1)([CH3:6])=[O:5])#[N:2].C(N=S(C1C=CC(N2C(=O)C3C(=CC=CC=3)C2=O)=NC=1)(C)=O)#[N:16]>>[C:1]([N:3]=[S:4]([C:7]1[CH:12]=[CH:11][C:10]([CH2:13][NH2:14])=[N:16][CH:8]=1)([CH3:6])=[O:5])#[N:2]

Participants

3

Reactant 2

HCID 86711611(4-(N-cyano-S-methylsulfonimidoyl)phenyl)methanamineHCID 867116252-(5-(N-Cyano-S-methylsulfonimidoyl)pyridin-2-yl)-isoindole-1,3-dione

Product 1

HCID 86711627(5-(N-Cyano-S-methylsulfonimidoyl)pyridin-2-yl)methanamine

Procedure

The title compound is prepared in analogy to preparation 6d, substituting 2-(4-(N-cyano-S-methylsulfonimidoyl)benzyl)isoindoline-1,3-dione with 2-(5-(N-cyano-S-methylsulfonimidoyl)pyridin-2-yl)-isoindole-1,3-dione (preparation 16d). ESI mass spectrum: [M+H]+=211; r.t. HPLC: 0.23 min (Z011_S03).

Workup

  1. customr.t

Sources & evidence

ORD record
ord-62c078375268414a962eee8c86eb6756
Source dataset
uspto-grants-2016_05
Patent number
US09346794B1

Reaction notes

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