HCID 86711621, compound → HCID 86711631, compound

HRID 527360Notes

Reaction equation

HRID 527360 reaction equation
FC1C=C(C=CC=1S(C)=[N:21][C:22]#[N:23])CN1C(=O)C2C(=CC=CC=2)C1=O.[C:25]([O:29][C:30](=[O:42])[NH:31][CH2:32][C:33]1[CH:38]=[CH:37][C:36]([S:39][CH3:40])=[CH:35][C:34]=1[F:41])([CH3:28])([CH3:27])[CH3:26]>>[C:25]([O:29][C:30](=[O:42])[NH:31][CH2:32][C:33]1[CH:38]=[CH:37][C:36]([S:39]([CH3:40])=[N:23][C:22]#[N:21])=[CH:35][C:34]=1[F:41])([CH3:28])([CH3:26])[CH3:27]

Participants

3

Reactant 2

HCID 86711621HCID 86711621, compoundHCID 86711630HCID 86711630, compound

Product 1

HCID 86711631HCID 86711631, compound

Procedure

The title compound is prepared following the procedure described for preparation 15b, using (2-fluoro-4-methylsulfanyl-benzyl)-carbamic acid tert-butyl ester (preparation 18b) as starting material. ESI mass spectrum: [M+H]+=312; r.t. HPLC: 0.68 min (5-95AB).

Workup

  1. customr.t

Sources & evidence

ORD record
ord-10f2702310734abd9be49aac2c92d5b0
Source dataset
uspto-grants-2016_05
Patent number
US09346794B1

Reaction notes

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