Triethylamine → HCID 131730600, compound

Participants

Reaction Steps

Triethylamine (7.36 mL, 52.82 mmol, 1.1 eq) was added at 0° C. to a stirred solution of N-BOC-1,4-phenylene diamine (10.00 g, 48.02 mmol, 1.0 eq) in CH3CN (240 mL), followed by 9-fluorenylmethyloxycarbonyl chloride (14.90 g, 57.62 mmol, 1.2 eq). The resulting mixture was allowed to come at room temperature. After 4 hours stirring at room temperature, the reaction mixture was filtered to afford 20.60 g of the crude expected product as a white powder which was used in the next step without any further purification.

Provenance & Evidence