化工社化工社 化学情報印刷レポート · 研究参考用
tert-Butyl (3-amino-4-fluorophenyl)carbamate → Tert-butyl (4-fluoro-3-((5-formyl-2-(methylthio)pyrimidin-4-yl)amino)phenyl)carbamate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-Butyl (3-amino-4-fluorophenyl)carbamate | HCID 11790890 | — |
| 反応物 | Tert-butyl (3-((5-formyl-2-(methylthio)pyrimidin-4-yl)amino)phenyl)carbamate | HCID 57343702 | — |
| 生成物 | Tert-butyl (4-fluoro-3-((5-formyl-2-(methylthio)pyrimidin-4-yl)amino)phenyl)carbamate | HCID 86732013 | — |
反応手順
The title compound was prepared according to the procedures described for Intermediate 50, starting from tert-butyl (3-amino-4-fluorophenyl)carbamate (58a; prepared according to the reported protocol in Kuramoto, Y. et al. J. Med. Chem. 2003, 46, 1905-1917).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09346801B2 |
| 出典データセット | uspto-grants-2016_05 |
| ORD ID | ord-f3f635878b4e4830a14a31b0091e706e |
| 出典メモ | uspto-grants-2016_05 |