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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 527778Generated: October 30, 2026

1,3-Dibromopropane → 2-(Butyloxy)-8-(methyloxy)-9-[3-(1-pyrrolidinyl)propyl]-9H-purin-6-amine

https://huagongshe.com/reaction/527778

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-DibromopropaneHCID 8001—
ReactantPyrrolidineHCID 31268—
ReactantHCID 178450357HCID 178450357—
Product2-(Butyloxy)-8-(methyloxy)-9-[3-(1-pyrrolidinyl)propyl]-9H-purin-6-amineHCID 59252595—

Reaction Steps

Prepared similarly to Intermediate 20 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate, 1,3-dibromopropane and pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09346806B2
Source datasetuspto-grants-2016_05
ORD IDord-8d3ed11ae3424ba9a22fd1975ea3ff78
Source noteuspto-grants-2016_05