Toluene → Quinoline

HRID 52793Notes

Reaction equation

HRID 52793 reaction equation
[NH2:1][C:2]1C(I)=C(C(O)=O)C(I)=C(C(O)=O)[C:7]=1I.[C:17]1([CH3:23])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[N:1]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:23]=[CH:7][CH:2]=1

Participants

3

Reactant 2

HCID 1140TolueneHCID 30157835-Amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid

Product 1

HCID 7047QuinolineYield 92.3%

Procedure

According to the procedure described in Example 1, the reaction is carried out with the same amounts of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid using toluene instead of meta-xylene, with quinoline, giving a yield of 92.3%.

Sources & evidence

ORD record
ord-6f92a03968894133bfc269ed02f0a814
Source dataset
uspto-grants-1997_04
Patent number
US05616795

Reaction notes

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