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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 527935Generated: October 31, 2026

Potassium Carbonate → HCID 86692154, compound

https://huagongshe.com/reaction/527935

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 68027531HCID 68027531—
SolventMethanolHCID 887—
ProductHCID 86692154HCID 86692154—

Reaction Steps

A mixture of (R)—N-(1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl)-N-methyl-5-((trimethylsilyl)ethynyl)pyridin-2-amine (26 mg, 0.06 mmol) and K2CO3 (20.0 mg) in MeOH (4.0 mL) was stirred at the ambient temperature for 16 hours. The volatiles were removed and the residue was purified by chromatography on silica gel to give the title compound. MS (m/z): 319 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09346810B2
Source datasetuspto-grants-2016_05
ORD IDord-c43ecfe1f6824599b2c91b6f54537925
Source noteuspto-grants-2016_05