HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 86692154, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 68027531 | HCID 68027531 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86692154 | HCID 86692154 | — |
Reaction Steps
A mixture of (R)—N-(1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl)-N-methyl-5-((trimethylsilyl)ethynyl)pyridin-2-amine (26 mg, 0.06 mmol) and K2CO3 (20.0 mg) in MeOH (4.0 mL) was stirred at the ambient temperature for 16 hours. The volatiles were removed and the residue was purified by chromatography on silica gel to give the title compound. MS (m/z): 319 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346810B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-c43ecfe1f6824599b2c91b6f54537925 |
| Source note | uspto-grants-2016_05 |