HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminophenol → HCID 22060588, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminophenol | HCID 11568 | — |
| Reactant | 2-chloro-N4-(3,5-dimethoxyphenyl)-5-fluoro-4-pyrimidineamine | HCID 22060694 | — |
| Product | HCID 22060588 | HCID 22060588 | — |
Reaction Steps
In like manner to the preparation of N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine, the reaction of 2-chloro-N4-(3,5-dimethoxyphenyl)-5-fluoro-4-pyrimidineamine with 3-hydroxyaniline gave N4-(3,5-dimethoxyphenyl)-N2-(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine. LCMS: ret. time: 18.98 min.; purity: 90%; MS (m/e): 357 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346765B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-6f177cf2037a45ed86579fb51bb4294d |
| Source note | uspto-grants-2016_05 |