Acetonitrile → HCID 89705144, compound

Participants

Reaction Conditions

Reaction Steps

The nitrile obtained from step 4 (1.21 g, 4.78 mmol) was dissolved in acetonitrile (9.95 mL, 191.3 mmol) and cooled to 0° C. Trifluoroacetic acid (7.1 mL, 96.63 mmol) was added dropwise. The solution was stirred overnight, concentrated and washed with ether (2×15 mL) to yield the crude product as an orange oily substance Yield: 2.00 g, 99%.

Provenance & Evidence