Azetidine → HCID 67458335, compound

HRID 528716Notes

Reaction equation

C(OC([N:8]1[CH2:22][CH:21]([CH3:23])[C:12]2=[C:13](O)[N:14]3[C:18]([N:19]=[C:11]2[CH2:10][CH2:9]1)=[CH:17][CH:16]=[N:15]3)=O)(C)(C)C.[NH:24]1[CH2:27][CH2:26][CH2:25]1>>[N:24]1([C:13]2[N:14]3[C:18]([N:19]=[C:11]4[CH2:10][CH2:9][NH:8][CH2:22][CH:21]([CH3:23])[C:12]=24)=[CH:17][CH:16]=[N:15]3)[CH2:27][CH2:26][CH2:25]1

Participants

Reactant 2

HCID 10422Azetidine

HCID 178430785HCID 178430785, compound

Product 1

HCID 67458335HCID 67458335, compound

Procedure

The product was prepared using 10-hydroxy-9-methyl-5,6,8,9-tetrahydro-1,4,7,10a-tetraaza-cyclohepta[f]indene-7-carboxylic acid tert-butyl ester in route 1 (from step c to f), in step e (route 1) azetidine was used as the amine.

Workup

customThe product was prepared

Sources & evidence

ORD record: ord-90c2a8ade3604982b1695d93a135a991
Source dataset: uspto-grants-2016_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09346816B2

Reaction notes

Loading…