HuagongsheHuagongshe Chemistry Print Report · For research reference only
10-Chloro-5,6,8,9-tetrahydro-1,4,7,10a-tetraaza-cyclohepta[f]indene-7-carboxylic acid tert-butyl ester → 10-[3-(4-Methyl-oxazol-2-yl)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 10-Chloro-5,6,8,9-tetrahydro-1,4,7,10a-tetraaza-cyclohepta[f]indene-7-carboxylic acid tert-butyl ester | HCID 46928122 | — |
| Reactant | 2-Azetidin-3-yl-4-methyl-oxazole | HCID 55300879 | — |
| Product | 10-[3-(4-Methyl-oxazol-2-yl)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene | HCID 67458771 | — |
Reaction Steps
The product was prepared using 10-chloro-5,6,8,9-tetrahydro-1,4,7,10a-tetraaza-cyclohepta[f]indene-7-carboxylic acid tert-butyl ester in route 1 (step e and f), in step e (route 1) 2-azetidin-3-yl-4-methyl-oxazole was used as the amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346816B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-16cfcb4ebb444af0be4cb9f9e0990f64 |
| Source note | uspto-grants-2016_05 |