Azetidine-3-carbonitrile hydrochloride → HCID 67458636, compound

HRID 528768Notes

Reaction equation

HRID 528768 reaction equation
C(OC([N:8]1[CH2:22][CH2:21][C:12]2=[C:13](Cl)[N:14]3[C:18]([N:19]=[C:11]2[CH2:10][CH2:9]1)=[CH:17][CH:16]=[N:15]3)=O)(C)(C)C.Cl.[NH:24]1[CH2:27][CH:26]([C:28]#[N:29])[CH2:25]1>>[N:15]1[N:14]2[C:18]([N:19]=[C:11]3[CH2:10][CH2:9][NH:8][CH2:22][CH2:21][C:12]3=[C:13]2[N:24]2[CH2:27][CH:26]([C:28]#[N:29])[CH2:25]2)=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 45072465Azetidine-3-carbonitrile hydrochlorideHCID 4692812210-Chloro-5,6,8,9-tetrahydro-1,4,7,10a-tetraaza-cyclohepta[f]indene-7-carboxylic acid tert-butyl ester

Product 1

HCID 67458636HCID 67458636, compound

Procedure

The product was prepared using 10-chloro-5,6,8,9-tetrahydro-1,4,7,10a-tetraaza-cyclohepta[f]indene-7-carboxylic acid tert-butyl ester in route 1 (step e and f), in step e (route 1) azetidine-3-carbonitrile hydrochloride was used as the amine.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-369aa2b028b14288b320c1aa0e587bfa
Source dataset
uspto-grants-2016_05
Patent number
US09346816B2

Reaction notes

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