HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine, 1-(3-chloropropyl)- → 7-(3-(Piperidin-1-yl)propoxy)naphthalene-2-sulfonic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine, 1-(3-chloropropyl)- | HCID 79625 | — |
| Reactant | Sodium 7-oxidonaphthalene-2-sulfonate | HCID 86718866 | — |
| Product | 7-(3-(Piperidin-1-yl)propoxy)naphthalene-2-sulfonic acid | HCID 86718874 | 30% |
Reaction Steps
Following a procedure analogous to that for the synthesis of Intermediate 26B, sodium 7-oxidonaphthalene-2-sulfonate (Pfaltz and Bauer, 200 mg, 0.75 mmol) and 1-(3-chloropropyl)piperidine (121 mg, 0.75 mmol) were converted to the title compound (78 mg, 30%). MS(ESI+) m/z 336.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346795B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-ea260d7f1f624948bb476786c2fe0972 |
| Source note | uspto-grants-2016_05 |