Butylamine → HCID 65710133, compound

HRID 528889Notes

Reaction equation

HRID 528889 reaction equation
[CH2:1]([NH2:5])[CH2:2][CH2:3][CH3:4].[F:6][C:7]([F:13])([F:12])[CH2:8][CH2:9][CH:10]=O>>[CH2:1]([NH:5][CH2:10][CH2:9][CH2:8][C:7]([F:13])([F:12])[F:6])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 8007ButylamineHCID 27770834,4,4-Trifluorobutanal

Product 1

HCID 65710133HCID 65710133, compound

Procedure

Following a procedure analogous to that for the synthesis of Example 106, butan-1-amine (293 mg, 4.00 mmol) and 4,4,4-trifluorobutanal (504 mg, 4.00 mmol) were converted to a crude oil which was used without purification. MS(ESI+) m/z 184.1 (M+H)+.

Workup

  1. customwas used without purification

Sources & evidence

ORD record
ord-df5d50c3522c4de88b556a429af0bd8f
Source dataset
uspto-grants-2016_05
Patent number
US09346795B2

Reaction notes

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