HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 71062222, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 71062294 | HCID 71062294 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 71062222 | HCID 71062222 | — |
Reaction Steps
To a solution of ethyl 4-(4-(tert-butoxycarbonyl)-2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)phenyl)-5-butyl-1-phenyl-1H-pyrazole-3-carboxylate (33 mg, 0.054 mmol) in DCM (2.0 mL) was added TFA (1.0 mL). After stirring at room temperature for 1 h, the reaction mixture was concentrated in vacuo. The residue was used directly in the next step without further purification. MS(ESI+) m/z 552.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346795B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-dd5e11353497489d8cdf0dd87618958b |
| Source note | uspto-grants-2016_05 |