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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 528966Generated: October 31, 2026

Trifluoroacetic acid → HCID 71062222, compound

https://huagongshe.com/reaction/528966

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 71062294HCID 71062294—
SolventDichloromethaneHCID 6344—
ProductHCID 71062222HCID 71062222—

Reaction Steps

To a solution of ethyl 4-(4-(tert-butoxycarbonyl)-2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)phenyl)-5-butyl-1-phenyl-1H-pyrazole-3-carboxylate (33 mg, 0.054 mmol) in DCM (2.0 mL) was added TFA (1.0 mL). After stirring at room temperature for 1 h, the reaction mixture was concentrated in vacuo. The residue was used directly in the next step without further purification. MS(ESI+) m/z 552.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09346795B2
Source datasetuspto-grants-2016_05
ORD IDord-dd5e11353497489d8cdf0dd87618958b
Source noteuspto-grants-2016_05