HCID 71060717, compound → HCID 71062231, compound

Participants

Reaction Steps

Following a procedure analogous to that for the synthesis of Intermediate 223E, (E)-methyl 3-(2-(2-ethoxy-2-oxoethylidene)hydrazinyl)benzoate (65 mg, 0.26 mmol) and tert-butyl 4-(2-nitrohex-1-enyl)-3-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)benzoate (120 mg, 0.26 mmol) were converted to the title compound (50 mg, 29%). MS(ESI+) m/z 666.3 (M+H)+.

Provenance & Evidence