HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86708889, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 86708891 | HCID 86708891 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86708889 | HCID 86708889 | — |
Reaction Steps
To a solution of methyl 1-(1-methyl-1H-pyrazol-4-yl)-1H-indole-3-carboxylate, TFA (3.5 mg, 9.48 μmol) in MeOH (95 μl) was added a solution of aq. KOH (33.2 μl, 0.066 mmol, 2 M). The reaction mixture was stirred at RT overnight, then acidified with 1N HCl. The solvent was evaporated under reduced pressure and the residue was dried under vacuum overnight. The title compound was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346829B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-41462f9bc752468089905cf0c231d464 |
| Source note | uspto-grants-2016_05 |