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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 529171Generated: October 25, 2026

Methyl iodide → 3-Methoxy-2-nitropyridine

https://huagongshe.com/reaction/529171

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantPotassium CarbonateHCID 11430—
Reactant3-Hydroxy-2-nitropyridineHCID 27057—
Product3-Methoxy-2-nitropyridineHCID 55606397.4%

Reaction Steps

The similar reaction as described in Reference Example 9 by using 2-nitro-3-hydroxypyridine (7.0 g), potassium carbonate (6.91 g) and methyl iodide (4.67 ml) gave the title compound (7.5 g) as crystalline powders.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09346822B2
Source datasetuspto-grants-2016_05
ORD IDord-5fbd7c38c66248e587ceea4b3a00c236
Source noteuspto-grants-2016_05