Hydrochloric Acid → HCID 86714688, compound

Participants

Reaction Conditions

Reaction Steps

To the compound obtained in step 1 were added 4N hydrochloric acid in 1,4-dioxane and water (1/1), and the mixture was stirred at 60° C. for 3 hours. The reaction mixture was concentrated under reduced pressure and the obtained residue was purified by high performance liquid chromatography (water-acetonitrile, each containing 0.1% trifluoroacetic acid) to give the title compound (2 steps yield 5%).

Provenance & Evidence