HuagongsheHuagongshe Chemistry Print Report · For research reference only
alpha-Bromo-o-chlorotoluene → (S)-3-Amino-1-(2-chlorobenzyl)azepan-2-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | alpha-Bromo-o-chlorotoluene | HCID 11905 | — |
| Reactant | (S)-3-amino-1-benzylazepan-2-one hydrochloride | HCID 68292429 | — |
| Product | (S)-3-Amino-1-(2-chlorobenzyl)azepan-2-one hydrochloride | HCID 68292357 | — |
Reaction Steps
(S)-3-Amino-1-(2-chlorobenzyl)azepan-2-one hydrochloride (270 mg, 0.934 mmol) was synthesized as described for the preparation of Intermediate 42 using 1-(bromomethyl)-2-chlorobenzene in step A. Anal. Calcd. for C18H25ClN2O3 m/z 352.8. found: 353.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346852B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-ced485d6b4684fe6b2c94d1b4fd32809 |
| Source note | uspto-grants-2016_05 |