Trifluoroacetic acid → HCID 68310556, compound

Participants

Reaction Steps

TFA (0.075 mL) was added to a solution of di-tert-butyl (1S,9S,1′S,9′S)-9,9′-(((2R,5R)-2,5-dibenzyl-1,6-dioxo-1,6-hexanediyl)diimino)bis(10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylate) (28 mg, 0.033 in DCM, 0.25 mL). The reaction mixture was stirred overnight at rt. The reaction mixture was concentrated and placed under vacuum to give (1S,9S,1′S,9′S)-9,9′-(((2R,5R)-2,5-dibenzyl-1,6-dioxo-1,6-hexanediyl)diimino)bis(10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid) (25 mg, 0.033 mmol, 100% yield). Anal. Calcd. for C40H52N6O8 m/z 744.8. found: 745.6 (M+H)+.

Provenance & Evidence