Triethylamine → HCID 86635088, compound

Participants

Reaction Steps

As in the synthesis of N-(2-azidoethyl)tetradecanamide, (E)-4-phenylbut-3-enoyl chloride (0.198 g, 1.19 mmol) was reacted with 2-azidoethanamine (0.114 g, 1.19 mmol) and triethylamine (0.239 g, 2.37 mmol) in dichloromethane (5 mL) to give (E)-N-(2-azidoethyl)-4-phenylbut-3-enamide (0.168 g, 55% yield). 1H NMR (300 MHz, CDCl3) δ 7.68 (d, J=15.6 Hz, 1H), δ 7.45 (d, J=3.3 Hz, 2H), δ 7.29 (m, 3H), δ 7.04 (t, J=4.1 Hz, 1H), δ 6.59 (d, J=15.9 Hz, 1H), δ 3.55 (q, J=6.0, 5.1 Hz, 2H), δ 3.47 (t, J=1.5 Hz, 2H) ppm; 13C NMR (75 MHz, CDCl3) δ 166.9, 141.6, 134.9, 130.1, 129.1, 128.1, 120.8, 51.1, 39.4 ppm; HRMS (ESI) calcd for C11H12N4O (M+) 216.1011. found 216.1005.

Provenance & Evidence