Triethylamine → HCID 57914398, compound

Participants

Reaction Steps

As in the synthesis of N-(2-azidoethyl)tetradecanamide, 4-tert-butylbenzoyl chloride (0.244 g, 1.23 mmol) was reacted with 2-azidoethanamine (0.106 g, 1.23 mmol) and triethylamine (0.249 g, 2.47 mmol) in dichloromethane (5 mL) to give N-(2-azidoethyl)-4-tert-butylbenzamide (0.221 g, 73% yield). 1H NMR (300 MHz, CDCl3) δ 7.73 (d, J=6.6 Hz, 2H), δ 7.43 (d, J=9.0 Hz, 2H), δ 6.95 (t, J=3.9 Hz, 1H), δ 3.59 (q, J=5.4, 5.7 Hz, 2H), δ 3.50 (t, J=5.1 Hz, 2H), δ 1.31 (s, 9H) ppm; 13C NMR (75 MHz, CDCl3) δ 168.2, 155.4, 131.4, 127.2, 125.8, 51.1, 39.7, 35.2, 31.4 ppm; HRMS (ESI) calcd for C13H18N4O (M+) 246.1480. found 246.1479.

Provenance & Evidence