6-chloro-2-N,4-N-dipropyl-1,3,5-triazine-2,4-diamine → N-(4,6-bis-propylamino-[1,3,5]triazin-2-yl)-N-isopropyl-hydroxylamine

HRID 530058Notes

Reaction equation

HRID 530058 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][CH2:9][CH2:10][CH3:11])[N:5]=[C:4]([NH:12][CH2:13][CH2:14][CH3:15])[N:3]=1.Cl.[CH:17]([NH:20][OH:21])([CH3:19])[CH3:18]>>[CH2:13]([NH:12][C:4]1[N:5]=[C:6]([NH:8][CH2:9][CH2:10][CH3:11])[N:7]=[C:2]([N:20]([CH:17]([CH3:19])[CH3:18])[OH:21])[N:3]=1)[CH2:14][CH3:15]

Participants

3

Reactant 2

HCID 183046-chloro-2-N,4-N-dipropyl-1,3,5-triazine-2,4-diamineHCID 170873N-Isopropylhydroxylamine Hydrochloride

Product 1

HCID 57377907N-(4,6-bis-propylamino-[1,3,5]triazin-2-yl)-N-isopropyl-hydroxylamineYield 61%

Procedure

2-Chloro-N-(4,6-bis-(n-propylamino)-[1,3,5]triazine (XXXIV) and N-isopropyl-hydroxylamine hydrochloride were reacted as described in Example 13 to yield N-(4,6-bis-propylamino-[1,3,5]triazin-2-yl)-N-isopropyl-hydroxylamine (LV) (61% yield). ESI-MS (m/z): 269 [M+H]+.

Sources & evidence

ORD record
ord-b74cbdb0a6f04a0889a91dd1be2c979b
Source dataset
uspto-grants-2016_05
Patent number
US09351972B2

Reaction notes

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