6-chloro-2-N,4-N-dipropyl-1,3,5-triazine-2,4-diamine → HCID 57377913, compound

HRID 530070Notes

Reaction equation

HRID 530070 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][CH2:9][CH2:10][CH3:11])[N:5]=[C:4]([NH:12][CH2:13][CH2:14][CH3:15])[N:3]=1.Cl.[CH2:17]([NH:19][O:20][CH:21]([CH3:23])[CH3:22])[CH3:18]>>[CH2:13]([NH:12][C:4]1[N:5]=[C:6]([NH:8][CH2:9][CH2:10][CH3:11])[N:7]=[C:2]([N:19]([CH2:17][CH3:18])[O:20][CH:21]([CH3:23])[CH3:22])[N:3]=1)[CH2:14][CH3:15]

Participants

3

Reactant 2

HCID 183046-chloro-2-N,4-N-dipropyl-1,3,5-triazine-2,4-diamineHCID 86665983HCID 86665983, compound

Product 1

HCID 57377913HCID 57377913, compoundYield 88%

Procedure

2-Chloro-N-(4,6-bis-(n-propylamino)-[1,3,5]triazine (XXXIV) was reacted with N-ethyl-O-isopropyl-hydroxylamine hydrochloride (LXXV) as described in Example 13, yielding N-(4,6-bis-propylamino-[1,3,5]triazin-2-yl)-N-ethyl-O-isopropyl-hydroxylamine (LXXVI) (88% yield). ESI-MS (m/z): 297 [M+H]+.

Sources & evidence

ORD record
ord-0d0704010262497985ca93bdb76b5d48
Source dataset
uspto-grants-2016_05
Patent number
US09351972B2

Reaction notes

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