HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Hydroxyphthalimide → HCID 21746216, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Hydroxyphthalimide | HCID 10665 | — |
| Reactant | 2,2-Difluoroethan-1-ol | HCID 136187 | — |
| Product | HCID 21746216 | HCID 21746216 | 52% |
Reaction Steps
N-Hydroxyphthalimide and 2,2-difluoro-ethanol were reacted as described for compound LXI in Example 27, affording XCVIII in 52% yield. 400 MHz 1H NMR (DMSO-d6, ppm) 7.92-7.85 (4H, m), 6.34 (1H, tt, J=54.4, 3.9 Hz), 4.46 (2H, td, J=14.1, 3.9 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09351972B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-4eb132b0e224444689799906f2457dc7 |
| Source note | uspto-grants-2016_05 |