Nitrogen → HCID 131735641, compound

Participants

Reaction Steps

According to a procedure similar to that of Preparation example 1, intermediate 2-nitro-4-(N-parafluorobenzyl-imino)-aniline was obtained by using o-nitro paraphenylene diamine and parafluorobenzaldehyde as starting materials. 2-nitro-4-(N-parafluorobenzyl-imino)-aniline (2.61 g, 0.01 mol) was dissolved in THF (30 mL) and air therein was replace with N2. Then Pd—C (10%, 261 mg) was rapidly added and N2 therein was replaced with H2. The hydrogenation reaction was conducted overnight, and the resulting reaction solution was filtered and concentrated to produce a product of 2-amino-4-(N-parafluorobenzyl-imino)-aniline (2.3 g, 99.6%, colorless oil, instable, prone to be oxidized and deteriorated), which was rapidly used in nest step. 1H NMR (300 MHz, CDCl3): δ 7.32 (t, J=8.7 Hz, 2H), 7.02 (t, J=8.7 Hz, 2H), 6.58 (d, J=8.7 Hz, 1H), 6.01-6.08 (m, 2H), 4.22 (s, 2H).

Provenance & Evidence