Methanol → HCID 178438903, compound

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Reaction Steps

2-{1-[4-Methyl-2-(4-nonylphenyl)thiazol-5-yl]ethylidenehydrazinecarboximid-amide (1f). Yellow solid (133 mg, 55%): mp 203-206° C. 1H NMR (DMSO-d6) δ 11.32 (brs, 1 H), 7.79 (d, J=8.1 Hz, 2 H), 7.60 (brs, 3 H), 7.28 (d, J=8.1 Hz, 2 H), 2.58 (m, 5 H), 2.41 (s, 3 H), 1.55 (m, 2 H), 1.22 (m, 12 H), 0.82 (t, J=6.9 Hz, 3 H); 13C NMR (DMSO-d6) δ 165.80, 156.87, 153.45, 147.99, 146.28, 131.19, 131.60, 129.44, 126.25, 36.34, 35.29, 31.60, 30.98, 29.28, 29.19, 28.99, 22.42, 18.46, 18.39, 14.27; ESIMS m/z (rel intensity) 400 (MH+, 100); HRESIMS, m/z 400.2540 MH+, calcd for C22H34N5S 400.2535; HPLC purity (methanol:water, 1:1): 95.40%.

Provenance & Evidence