Trifluoroacetic acid → HCID 86663117, compound

Participants

Reaction Steps

To tert-butyl 4-(N-methyl-4-(pyridin-3-yl)-1H-imidazole-1-carboxamido)piperidine-1-carboxylate (500 mg, 1.297 mmol) was added trifluoroacetic acid (4 mL, 51.9 mmol) to give a turbid solution. The mixture was allowed to stir at room temperature for 1 h, whereupon the solvent was removed by evaporation. The oily residue was triturated with ether, and the resulting white solid was filtered off to give a white solid (653.2 mg, 88% yield).

Provenance & Evidence