4-Nitrobenzyl bromide → HCID 19036242, compound

HRID 53048Notes

Reaction equation

[CH3:1][C:2]1[NH:3][C:4]([C:12]([O:14][CH2:15][CH3:16])=[O:13])=[C:5]([C:7]([O:9][CH2:10][CH3:11])=[O:8])[N:6]=1.[N+:17]([C:20]1[CH:27]=[CH:26][C:23]([CH2:24]Br)=[CH:22][CH:21]=1)([O-:19])=[O:18]>>[CH3:1][C:2]1[N:6]([CH2:24][C:23]2[CH:26]=[CH:27][C:20]([N+:17]([O-:19])=[O:18])=[CH:21][CH:22]=2)[C:5]([C:7]([O:9][CH2:10][CH3:11])=[O:8])=[C:4]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[N:3]=1

Participants

Reactant 2

HCID 660114-Nitrobenzyl bromide

HCID 653376ST4058398

Product 1

HCID 19036242HCID 19036242, compoundYield 80.7%

Procedure

Following a procedure similar to that described in Preparation 42(i), but using 6.65 g of diethyl 2-methylimidazole-4,5-dicarboxylate and 6.35 g of p-nitrobenzyl bromide as starting materials, 8.57 g of the title compound were obtained as crystals, melting at 109° C.

Sources & evidence

ORD record: ord-b8149721385345a992751b68c19823f4
Source dataset: uspto-grants-1997_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05616599

Reaction notes

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